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Transdermal fentanyl (Duragesic and generic) has limited use for treatment of chronic pain. Transdermal fentanyl is a short-acting opioid packaged in a long-acting delivery system, making patients on it especially prone to development of opioid tolerance.

Monitor all patients on controlled substances by checking the state prescription drug monitoring program report with each prescription. Perform periodic urine drug testing. Pill counts are appropriate for the highest risk patients.

In some cases, underlying neurobiologic mechanisms may be overlapping, and more than one pain syndrome may be present.

A primary psychiatric condition may contribute to the worsening of chronic pain. Also, psychiatric conditions may develop secondary to chronic pain.

Chronic pain has little in common with acute pain and should be considered as a separate medical condition. Some differences are:

Many patients are aware that methadone is often associated with opioid addiction therapy. Patients may need additional counseling that methadone is an effective analgesic, not merely a treatment for opioid addiction.

Pain intensity. A patient’s report of pain intensity provides a subjective gauge of the distraction and interference pain causes in their daily life.

Nodules or swellings – these lumps can stop the thyroid gland from working properly, or are simply uncomfortable.

Consider buprenorphine. For patients with opioid use disorder, conversion from other opioids to buprenorphine can provide a safer alternative while still providing the benefits, if any, of opioid analgesia. This can be done by a prescriber with a XDEA, with input from other specialists as needed.

Compounded topical 5% morphine can provide local wound analgesia and may promote healing. It is only available at compounding pharmacies and can be expensive.

A Mediterranean-adjacent diet that focuses on antioxidants, fiber, and healthy fats is most likely to be liver protective and generally good for you. “That said, I always encourage my clients to follow the 80/20 more info rule: nourish your body with whole foods most of the time and leave room for flexibility and enjoyment without guilt,” says Dr. Morris-Stiff. “It’s about what you do consistently, not occasionally.”

“The liver naturally eliminates toxins from the body and does not require a special diet or cleanse,” says Menning. “To keep it healthy, focus on a balanced diet of whole grains, fruits, vegetables, lean protein, and healthy fats as well as engaging in regular physical activity.”

" Oral antibiotics are usually prescribed for moderate to severe acne, and you'll need to take them for somewhere between one and three months. They're often prescribed with a topical medication that you can continue to use after finishing the antibiotic.

The goal of physical therapy is to improve function. Therapeutic exercise, other modalities, manual techniques, and patient education are part of a comprehensive treatment program to accomplish this goal.

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